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Tissue Restoration Lab

Modulating Ion Channels for Superior Tissue Restoration via Immuneregulation (MISTRI)

TRL

Tissue Restoration Lab is dedicated to develop therapeutic products across the entire spectrum of Technology Readiness Levels from ideation, validation to commercialization.

We are a translational research group focused on developing novel therapeutic solutions for various diseases by targeting ion channels. We characterize the expression and function of lysosomal, mitochondrial, plasma-membrane bound ion channels of immune cells, bone cells and sperm under physiological and pathological states. We genetically and pharmacologically modulate ion channel signalling to improve cellular function.

PROJECTS

NK Immune synapse

MISTRI

MISTRI

Modulating Ion channels for Superior Tissue Restoration via Immune regulation

Wound Healing

IMPACT

IMPACT

Investigating Modulation of Pressure Activated Channels for Tissue Restoration

NK Tubulin and Lysosomes

INFINITY

INFINITY

Ion channels in Infection and Immunity

Mito-ER contacts

FRICTION

FRICTION

Ion channels in Fertility and Contraception

hTERT Mito A1

TACTIC

TACTIC

Tailoring Anti-Cancer Therapy via Immunomodulatory Channels

Mito-Lyso contacts

SHANTI

PLAN-O

Specialized Hydrogels and Nanoformulations for Therapeutic Interventions 

GALLERY

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